Studies on Complement Fixation in Tuberculosis. Iii
نویسنده
چکیده
The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with high dilution of the normal blood serum of a number of species. The precipitation reaction presents as a peculiar feature a very long pro-zone and is further dependent on a preceding heat treatment of the serum for its demonstration. Occurring as a reaction of normal serum, the reaction is apparently not influenced by immunization sufficient to develop moderate specific complement fixation reactions.
منابع مشابه
Complement Fixation in Kala-Azar with the WKK Antigen
In our present issue we publish two articles in which the value of a complement-fixation test in early diagnosis of kala-azar is stressed. The antigen used is that of Witebsky, Klingenstein and Kuhn prepared from the tubercle bacillus, and originally intended for complement-fixation tests in tuberculosis. In tuberculosis, however, the results are very poor. Work in South America, however, revea...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 45 شماره
صفحات -
تاریخ انتشار 2003